What Semax / Selank / DSIP Blend actually is

This protocol combines three cognitive peptides: Semax (ACTH analogue, daytime cognitive and mood effects), Selank (anxiolytic tuftsin analogue, daytime resilience), and DSIP (delta sleep-inducing peptide, nighttime architecture). Semax and Selank are administered intranasally; DSIP is subcutaneous pre-sleep.¹

The protocol addresses cognition across the 24-hour cycle: daytime focus and mood (Semax), daytime anxiolysis (Selank), and nighttime sleep depth (DSIP). It is the most comprehensive cognitive peptide protocol we prescribe.²

At Luxbae, Semax / Selank / DSIP Blend is prescribed and supervised by Dr. Ernst von Schwarz, MD, PhD after a complimentary medical consultation.

Mechanism — 24-hour cognitive coverage

Semax (BDNF/NGF, monoamine modulation), Selank (GABAergic anxiolysis), DSIP (delta-wave architecture).¹

What the research shows

Daytime cognition. Semax-driven attention and processing speed effects.¹

Anxiety reduction. Selank’s non-sedating anxiolysis through the day.

Sleep depth. DSIP’s delta-wave amplitude effects at night.

Side effects: Generally well-tolerated cumulatively. Mild nasal irritation (intranasal), occasional vivid dreams.

FDA note: None of the components is FDA-approved in the US. Semax and Selank are approved in Russia.

Semax / Selank / DSIP Blend FAQ

Three peptides — too much?
Most patients tolerate well; we can simplify if components aren’t tolerated.

Order of administration?
Semax/Selank AM; DSIP PM.

References

1. Kaplan AYa, et al. Semax nootropic activity. Neurosci Res Commun. 1996.
2. Zozulia AA, et al. Selank anxiolytic mechanisms. Zh Nevrol Psikhiatr. 2008.
3. Schoenenberger GA, Monnier M. DSIP. Proc Natl Acad Sci USA. 1977;74(3):1282-1286.